COURSE “EPIDEMIOLOGY AND BIOSTATISTICS IN COPC”

June 14-25, 2004

Week one. Epidemiology.

June 14.

10.00-10.30 School opening and registration.

10.30-11.00 Introduction to Community-Oriented Primary Care. S.L.Plavinski (MAPS)

11.30-12.00 What is epidemiology. G.Balasanjanc (MAPS)

12.00-12.30 Coffee-break

12.30-15.00 Epidemiology as a basis for medical sciences and decision-making in health care. Sources of data. – C.Ortendahl (Karolinska Institute)

15.00-17.00 Causality in epidemiology. S.L.Plavinski

June 15

10.00 – 11.00 Epidemiology, medical science and resource allocation – question of ethics. C. Ortendahl.

11.00-12.00 Types of studies in epidemiology. S.L.Plavinski

12.00-12.30 Coffee-break

12.30-14.00 Cohort studies. S.L.Plavinski

14.00-16.30 Case-control studies and other types of epidemiological studies. Study validity and bias. T.Dubikaitis (MAPS)

16.30-17.00 Workgroups

June 16

10.00-12.00 Randomized controlled trials. Organization and types. S.L.Plavinski

12.00-12.30 Coffee-break

12.30-15.00 Planning of RCT. Non-equivalent group designs. Regression-discontinuity trials. S.L.Plavinski

15.00-16.30 Ethical problems of RCT and human experimentation. I.Batrakova (MAPS)

16.30-17.00 Workgroups

June 17

10.00-12.00 Epidemiology of infectious diseases. Epidemiological surveillance. Outbreak investigation. V. Savina (MAPS)

12.00-12.30 Coffee-break

12.30-14.30 Epidemiology of tuberculosis. G. Balasanjanc

14.30-16.30 Introduction to mathematical epidemiology of infectious diseases. S.Plavinski

16.30-17.00 Workgroups

June 18

10.00-11.00 Epidemiology of STD. A.Barinova (MAPS)

11.00-12.00 Epidemiology of non-infectious diseases. Contrasts with infections. S.L.Plavinski

12.00-12.30 Coffee-break

12.30-14.00 Epidemiology of CVD. Historical sketch. Study of biological and behavioral risk factors. S.Plavinski

14.00-15.30 Maternal mortality. Epidemiological view. Study of cosial risk factors. N.Gurina (MAPS)

15.30-17.00 Epidemiology and oncology. Study of environmental risk factors. A. Lebedev (MAPS)

Week two. Biostatistics

June 21

10.00-12.00 Introduction to the biostatistics course and to Biostatistics M.Reilly & Y.Pawitan (Karolinska Institute, Sweden)

12.00-12.30 Coffee-break

12.30-13.30 Introduction to the computer lab and to Stata M.Reilly & Y.Pawitan

13.30-15.30 Lecture: Summarising & Presenting Data M.Reilly & Y.Pawitan

15.30-17.00 Lab: Introduction to Stata, data summaries and graphical presentation M.Reilly & Y.Pawitan

June 22

10.00-12.00 Lecture: Probability Distribution & Sampling Distribution M.Reilly & Y.Pawitan

12.00-12.30 Coffee-break

12.30-13.30 Lab: Confidence intervals & hypothesis tests for a mean M.Reilly & Y.Pawitan

13.30-15.30 Lecture: Estimating & Testing a proportion M.Reilly & Y.Pawitan

15.30-17.00 Lab: Confidence Interval for Proportions M.Reilly & Y.Pawitan

June 23

10.00-12.00 Lecture: Comparing two groups M.Reilly & Y.Pawitan

12.00-12.30 Coffee-break

12.30-13.30 Lab: Comparison of means and proportions M.Reilly & Y.Pawitan

13.30-15.30 Lecture: Rates and risks, confidence intervals for RR and OR, in-class exercises M.Reilly & Y.Pawitan

15.30-17.00 Lab: RR and ORs M.Reilly & Y.Pawitan

June 24

10.00-12.00 Lecture: Confounding & Adjusted OR Exercises: interpreting adjusted ORs in published papers M.Reilly & Y.Pawitan

12.00-12.30 Coffee-break

12.30-13.30 Lab: Adjusted OR M.Reilly & Y.Pawitan

13.30-15.30 Lecture: Power & sample size M.Reilly & Y.Pawitan

15.30-17.00 Lab: Power & sample size M.Reilly & Y.Pawitan

June 25

10.00-12.00 Biostatistics in epidemiology, science and decision-making. S.L.Plavinski

12.00-12.30 Coffee-break

12.30-13.30 Biostatistics in COPC. S.L.Plavinski

13.30-15.00 Self-work with Stata

15.00-16.30 Exam