THE COURSE "EVIDENCE-BASED MEDCINE AND HEALTH TECHNOLOGY ASSESSMENT"

November 26 - December 7, 2001

The program

Monday, November 26 (Prof. S.Plavinski & Prof. O.Kuznetsova)

9.30 - 10.00 Registration

10.00 - 10.15 Opening of the course

10.15 - 10.30 Icebreaking for students

10.30 - 11.00 Introduction to course

11.00 - 11.30 Evidence-based medicine. What it is and what it isn't

11.30 - 12.00 Coffee-break

12.00 - 13.00 Basic sciences of EBM: Clinical epidemiology. Population. Patients. Normality. Tests.

13.00 - 13.30 Group work

13.30 - 14.30 Lunch

14.30 - 15.30 Basic Sciences of EBM: Biostatistics.

15.30 - 16.30 Group work

Tuesday, November 27 (Prof. S.Plavinski)

10.00 - 11.00 Introduction to EBM: EBM process. Clinically important question.

11.00 - 11.30 Groupwork

11.30 - 12.00 Coffee-break

12.00 - 13.00 Information search. General approach. Bibliographical databases. PubMed. MESH terms. Sesnsitive and specific search.

13.00 - 13.30 Reformulating clinical questions into PubMed search language. Groupwork

13.30 - 14.30 Lunch

14.30 - 15.30 Asssessment of the evidences. I. Natural history and prognosis articles. NNH

15.30 - 16.00 Assessment of the evidences II. Diagnosis

16.00 - 17.00 Groupwork

Wednsday, November 28 (prof. E.Jonsson)

9.30 -16.00 Introduction to HTA, Including

11.30 - 12.00 Coffee-break

13.30 - 14.30 Lunch

16.00-17.00 Groupwork

Thirsday, November 29 (prof. E. Jonsson)

9.30 - 16.00 Introduction to economic evaluation, Including

11.30 - 12.00 Coffee-break

13.30 - 14.30 Lunch

16.00-17.00 Groupwork

Friday, November 30

9.30 - 10.30 International Collaboration in HTA (Yu.Shamova)

10.30 - 11.30 Development of EBM in Russia (E.Novichkova)

11.30 - 12.00 Coffee-break

12.00 - 12.30 Resource center at MMA. Projects (E.Novichkova)

12.30 - 13.00 Development of EBM at MAPS (T.Dubikaitis)

13.00-13.30 Groupwork

13.30 - 14.30 Lunch

14.30 - 16.00 Asssessment of the evidences III. Etiology

16.00 - 17.00 Groupwork

Monday, December 3

10.00 - 11.30 EBM tools. Introduction to systematic reviews. Prof. V.Vlasov

11.30 - 12.00 Coffee-break

12.00 - 13.30 Asssessment of the evidences IV. Therapy. NNT. S.Varshavsky

13.30 - 14.30 Lunch

14.30 - 15.00 Cochrane collaboration. Goals and tasks. V.Vlasov and S. Varshavsky

15.00 - 16.00 Doing own research. Planning of experiment. Error types. Number of study participants.

16.00 - 17.00 Groupwork

Tuesday, December 4 (prof. S.Plavinski)

10.00 -11.30 Introduction to meta-analysis. Data collection & graphical methods

11.30 - 12.30 Coffee - break

12.30 - 13.30 Statistical methods of meta-analysis I. Common effect size estimation.

13.30 - 14.30 Lunch

14.30 - 16.00 Statistical methods of meta-analysis II. Heterogenity. Subgroup analysis. SAS system for meta-analysis

16.00 - 17.00 Groupwork

Wednsday, December 5 (Prof. S.Plavinski)

10.00 - 11.30 Introduction to clinical decision analysis. Game theory. Utility. Utility elicitation.

11.30 - 12.00 Coffee-break

12.00 - 13.30 Clinical Decsion Analysis I. Classical methods: Decision trees, threshold proability, NNT/NNH

13.30 - 14.30 Lunch

14.30 - 16.00 Multiattribute Decision Analysis Models and Time-dependent course: Analytical Hierarchical Process. Markov modelling. Estimation of QALY from Markov modes. Computerzed analysis. Decision analysis for health managers.

16.00 - 17.00 Groupwork

Thirsday, December 6.

10.00 - 11.30 Introduction to scientific writing T.Dubikaitis

11.30 - 12.30 Coffee break

12.30 - 13.30 Scientific writing, cntd...

13.30 - 14.30 Lunch

14.30 - 16.00 Ethical problems in EBM/HTA

16.00 - 17.00 Groupwork

Friday, Dcember 7

10.00 - 11.30 Clinical guidelines. Grading of evidences. Prof. O.Kuznetsova

11.30 - 12.00 Coffee-break

12.00 - 13.30 Exam

13.30 - 14.30 Lunch

14.30 - 16.00 Roundtable discussion of EBM and HTA. Discussion of the course. What do we need to implement EBM?